Article Details


Cancer Bioinformatics for Updating Anticancer Drug Developments and Personalized Therapeutics

[ Vol. 12 , Issue. 2 ]

Author(s):

Da-Yong Lu, Rong-Xin Qu, Ting-Ren Lu and Hong-Ying Wu   Pages 101 - 110 ( 10 )

Abstract:


Background: Last two to three decades, this world witnesses a rapid progress of biomarkers and bioinformatics technologies. Cancer bioinformatics is one of such important omics branches for experimental/clinical studies and applications.

Methods: Same as other biological techniques or systems, bioinformatics techniques will be widely used. But they are presently not omni-potent. Despite great popularity and improvements, cancer bioinformatics has its own limitations and shortcomings at this stage of technical advancements.

Results: This article will offer a panorama of bioinformatics in cancer researches and clinical therapeutic applications-possible advantages and limitations relating to cancer therapeutics. A lot of beneficial capabilities and outcomes have been described. As a result, a successful new era for cancer bioinformatics is waiting for us if we can adhere on scientific studies of cancer bioinformatics in malignant- origin mining, medical verifications and clinical diagnostic applications.

Conclusion: Cancer bioinformatics gave a great significance in disease diagnosis and therapeutic predictions. Many creative ideas and future perspectives are highlighted.

Keywords:

Cancer bioinformatics, cancer stem cells, cancer therapy, drug developments, drug response predictions, neoplasm metastasis, personalized cancer therapy.

Affiliation:

Shanghai University, Shanghai 200444, Nanjing General Hospital of Nanjing Military Command, Jiangsu Province, Shanghai University, Shanghai 200444, Shanghai University, Shanghai 200444

Graphical Abstract:



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